Single-Dose Gamma-Irradiation Induces Up-Regulation of Chemokine Gene Expression and Recruitment of Granulocytes into the Portal Area but Not into Other Regions of Rat Hepatic Tissue

Liver damage is a serious clinical complication of γ-irradiation. We therefore exposed rats to single-dose γ-irradiation (25 Gy) that was focused on the liver. Three to six hours after irradiation, an increased number of neutrophils (but not mononuclear phagocytes) was observed by immunohistochemist...

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Main Authors: Malik, Ihtzaz Ahmed, Moriconi, Federico, Sheikh, Nadeem, Naz, Naila, Khan, Sajjad, Dudas, Jozsef, Mansuroglu, Tümen, Hess, Clemens Friedrich, Rave-Fränk, Margret, Christiansen, Hans, Ramadori, Giuliano
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843471/
https://ncbi.nlm.nih.gov/pubmed/20185578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090505
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