Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers.
Previously a cloned emetine-resistant mutant of the protozoal parasite Entamoeba histolytica was shown to overexpress a gene for an ameba homolog of the mammalian P-glycoprotein, a plasma membrane pump that removes hydrophobic drugs from multidrug-resistant tumor cells. Three sets of experiments wer...
Shranjeno v:
| izdano v: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1992
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1283295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2392 |
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