Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics

We describe a method to measure protein synthesis and catabolism in humans without prior purification and use the method to measure the turnover of surfactant protein-B (SP-B). SP-B, a lung-specific, hydrophobic protein essential for fetal-neonatal respiratory transition, is present in only picomola...

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Detalhes bibliográficos
Main Authors: Tomazela, Daniela, Patterson, Bruce W., Hanson, Elizabeth, Spence, Kimberly L., Kanion, Tiffany B., Salinger, David H., Vicini, Paolo, Barret, Hugh, Heins, Hillary B., Cole, F. Sessions, Hamvas, Aaron, MacCoss, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843406/
https://ncbi.nlm.nih.gov/pubmed/20178338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1001433
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