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Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity
Regeneration of visual chromophore in the vertebrate visual cycle involves the retinal pigment epithelium-specific protein RPE65, the key enzyme catalyzing the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol. Although RPE65 has no predicted membrane spanning domai...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843217/ https://ncbi.nlm.nih.gov/pubmed/20100834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063941 |
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