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Comparative pharmacokinetics of amphotericin B after administration of a novel colloidal delivery system, ABCD, and a conventional formulation to rats.

The pharmacokinetics and tissue distribution of two amphotericin B dosage forms were compared in rats. A novel lipid-based colloidal delivery system for amphotericin B (Amphotericin B Colloidal Dispersion [ABCD]) which reduces the toxicity of amphotericin B in animals was compared with a conventiona...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Fielding, R M, Smith, P C, Wang, L H, Porter, J, Guo, L S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284312/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.6.1208
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