Imipenem- and meropenem-resistant mutants of Enterobacter cloacae and Proteus rettgeri lack porins.

Carbapenems such as imipenem and meropenem are not rapidly hydrolyzed by commonly occurring beta-lactamases. Nevertheless, it was possible, by mutagenesis and selection, to isolate mutant strains of Enterobacter cloacae and Proteus rettgeri that are highly resistant to meropenem and imipenem. Two al...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Raimondi, A, Traverso, A, Nikaido, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284306/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.6.1174
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