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Beta-lactam antibiotics potentiate magainin 2 antimicrobial activity in vitro and in vivo.

The ability of magainin 2 to augment antibiotic therapy was examined. Susceptibility to magainin 2 was determined on Escherichia coli incubated in the presence and absence of sublethal concentrations of antibiotics both in vitro and in vivo. Experiments in buffer and normal human serum revealed that...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Darveau, R P, Cunningham, M D, Seachord, C L, Cassiano-Clough, L, Cosand, W L, Blake, J, Watkins, C S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.6.1153
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