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A versatile 3D culture model facilitates monitoring of astrocytes undergoing reactive gliosis

A major impediment to CNS repair is the glial scar, which forms following damage and is composed mainly of ramified, ‘reactive’ astrocytes that inhibit neuronal regrowth. The transition of astrocytes into this reactive phenotype (reactive gliosis) is a potential therapeutic target, but glial scar fo...

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Detalhes bibliográficos
Main Authors: East, Emma, Golding, Jonathan P, Phillips, James B
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842570/
https://ncbi.nlm.nih.gov/pubmed/19813215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.209
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