Rs5848 variant influences GRN mRNA levels in brain and peripheral mononuclear cells in patients with Alzheimer's disease

Mutations in the progranulin gene (GRN) are causative for Frontotemporal Lobar Degeneration with ubiquitin-immunoreactive neuronal inclusions (FTLD-U). However, additional studies have demonstrated that these variants could be associated with Alzheimer's disease (AD). The influence of GRN genet...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Fenoglio, Chiara, Galimberti, Daniela, Cortini, Francesca, Kauwe, John S.K., Cruchaga, Carlos, Venturelli, Eliana, Villa, Chiara, Serpente, Maria, Scalabrini, Diego, Mayo, Kevin, Piccio, Laura M., Clerici, Francesca, Albani, Diego, Mariani, Claudio, Forloni, Gianluigi, Bresolin, Nereo, Goate, Alison M., Scarpini, Elio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842455/
https://ncbi.nlm.nih.gov/pubmed/19625741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1170
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi