Comparison of N-methylthiotetrazole dispositions in healthy volunteers following single intravenous doses of moxalactam, cefoperazone, and cefotetan.

The N-methylthiotetrazole side chain (NMTT) that is present on several cephalosporins has been implicated in the development of antibiotic-associated hypoprothrombinemia. A randomized three-way crossover trial was conducted to compare the release of the NMTT side chain from three NMTT-containing ant...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Welage, L S, Hejmanowski, L G, Wilton, J H, Walawander, C, Rigan, D, Williams, J S, Schentag, J J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2764537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.6.857
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