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Nerve Terminal Degeneration Is Independent of Muscle Fiber Genotype in SOD1(G93A) Mice

BACKGROUND: Motor neuron degeneration in SOD1(G93A) transgenic mice begins at the nerve terminal. Here we examine whether this degeneration depends on expression of mutant SOD1 in muscle fibers. METHODOLOGY/PRINCIPAL FINDINGS: Hindlimb muscles were transplanted between wild-type and SOD1(G93A) trans...

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Detalhes bibliográficos
Main Authors: Carrasco, Dario I., Bichler, Edyta K., Seburn, Kevin L., Pinter, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842435/
https://ncbi.nlm.nih.gov/pubmed/20339550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009802
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