Dose-dependent pharmacokinetics of mezlocillin in rats.
The pharmacokinetics of mezlocillin were examined in rats following bolus intravenous doses of 20 or 200 mg/kg. Mezlocillin exhibited bi- or triexponential disposition profiles, and the area under the concentration-time curve increased nonproportionally with dose similar to reported findings in huma...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2764534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.6.839 |
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