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Induction of long-term depression and rebound potentiation by inositol trisphosphate in cerebellar Purkinje neurons

Cerebellar Purkinje neurons receive two major excitatory inputs, the climbing fibers (CFs) and parallel fibers (PFs). Simultaneous, repeated activation of CFs and PFs results in the long-term depression (LTD) of the amplitude of PF-evoked synaptic currents. To induce LTD, activation of CFs may be su...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Khodakhah, Kamran, Armstrong, Clay M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28423/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.14009
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