APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

Apolipoprotein (apo) C-I is a constituent of chylomicrons, very low density lipoprotein, and high density lipoprotein. The role of apo C-I in human metabolism is incompletely defined. We took advantage of a naturally occurring amino acid polymorphism that is present in aboriginal North Americans, na...

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Main Authors: Lahiry, Piya, Cao, Henian, Ban, Matthew R., Pollex, Rebecca L., Mamakeesick, Mary, Zinman, Bernard, Harris, Stewart B., Hanley, Anthony J. G., Huff, Murray W., Connelly, Philip W., Hegele, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2010
Teme:
Patient-Oriented and Epidemiological Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842156/
https://ncbi.nlm.nih.gov/pubmed/19812053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P002014
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