Photoactivable sphingosine as a tool to study membrane microenvironments in cultured cells

Human fibroblasts from normal subjects and Niemann-Pick A (NPA) disease patients were fed with two labeled metabolic precursors of sphingomyelin (SM), [(3)H]choline and photoactivable sphingosine, that entered into the biosynthetic pathway allowing the synthesis of radioactive phosphatidylcholine an...

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Bibliografiske detaljer
Main Authors: Aureli, Massimo, Prioni, Simona, Mauri, Laura, Loberto, Nicoletta, Casellato, Riccardo, Ciampa, Maria Grazia, Chigorno, Vanna, Prinetti, Alessandro, Sonnino, Sandro
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842147/
https://ncbi.nlm.nih.gov/pubmed/19820263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001974
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