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Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

Cisplatin is one of the most commonly used anticancer drugs. It kills cancer cells by damaging their DNA, and hence cellular DNA repair capacity is an important determinant of its efficacy. Here, we investigated the repair of cisplatin-induced DNA damage in mouse liver and testis tissue extracts pre...

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Bibliografiske detaljer
Main Authors: Kang, Tae-Hong, Lindsey-Boltz, Laura A., Reardon, Joyce T., Sancar, Aziz
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841896/
https://ncbi.nlm.nih.gov/pubmed/20304803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915085107
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