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Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

Cisplatin is one of the most commonly used anticancer drugs. It kills cancer cells by damaging their DNA, and hence cellular DNA repair capacity is an important determinant of its efficacy. Here, we investigated the repair of cisplatin-induced DNA damage in mouse liver and testis tissue extracts pre...

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Detalhes bibliográficos
Main Authors: Kang, Tae-Hong, Lindsey-Boltz, Laura A., Reardon, Joyce T., Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841896/
https://ncbi.nlm.nih.gov/pubmed/20304803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915085107
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