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An unlocking/relocking barrier in conformational fluctuations of villin headpiece subdomain

A reversible structural unlocking reaction, in which the close-packed van der Waals interactions break cooperatively, has been found for the villin headpiece subdomain (HP35) using triplet-triplet-energy transfer to monitor conformational fluctuations from equilibrium. Unlocking is associated with a...

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Detalhes bibliográficos
Main Authors: Reiner, Andreas, Henklein, Peter, Kiefhaber, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841885/
https://ncbi.nlm.nih.gov/pubmed/20194774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910001107
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