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Reprogramming mRNA translation during stress

The survival of mammalian cells exposed to adverse environmental conditions, requires a radical reprogramming of protein translation. Stress-activated kinases target components of the initiation machinery (e.g., eIF2α, eIF4E-BP, eIF4B, and ribosomal protein S6) to inhibit the translation of “houseke...

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Detalhes bibliográficos
Main Authors: Yamasaki, Satoshi, Anderson, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841789/
https://ncbi.nlm.nih.gov/pubmed/18356035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.01.013
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