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Reprogramming mRNA translation during stress
The survival of mammalian cells exposed to adverse environmental conditions, requires a radical reprogramming of protein translation. Stress-activated kinases target components of the initiation machinery (e.g., eIF2α, eIF4E-BP, eIF4B, and ribosomal protein S6) to inhibit the translation of “houseke...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841789/ https://ncbi.nlm.nih.gov/pubmed/18356035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.01.013 |
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