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EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway

Latent membrane protein 2A (LMP2A) of Epstein Barr virus (EBV) provides developmental and survival signals that mimic those of a B cell receptor (BCR). Expression of LMP2A during B cell development results in the ability of B cells to exit the bone marrow in the absence of a BCR and persist in the p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anderson, Leah J, Longnecker, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841786/
https://ncbi.nlm.nih.gov/pubmed/18559925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/001461-0
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