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PPi analogs as inhibitors of human T-lymphotropic virus type III reverse transcriptase.

Twenty-six PPi analogs were tested for inhibitory effects on human T-lymphotropic virus type III reverse transcriptase. The structural requirements for inhibition and mechanism of action of the most active inhibitors have been investigated. Foscarnet (phosphonoformic acid) was the most potent inhibi...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Vrang, L, Oberg, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284169/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2425731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.5.867
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