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Cleft Palate Is Caused by CNS Dysfunction in Gad1 and Viaat Knockout Mice
BACKGROUND: Previous studies have shown that disruption of GABA signaling in mice via mutations in the Gad1, Gabrb3 or Viaat genes leads to the development of non-neural developmental defects such as cleft palate. Studies of the Gabrb3 and Gad1 mutant mice have suggested that GABA function could be...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841638/ https://ncbi.nlm.nih.gov/pubmed/20333300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009758 |
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