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Improved synthesis of a fluorogenic ceramidase substrate
Substantial interest has focused on the roles of sphingolipid metabolizing enzymes in a variety of hyperproliferative and inflammatory diseases. A key family of enzymes involved in these pathologies is the ceramidases. Ceramidases cleave the pro-apoptotic lipid ceramide into a long-chain fatty acid...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841511/ https://ncbi.nlm.nih.gov/pubmed/20085856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.071 |
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