BRL-36650: in vitro studies and assessment of serum bactericidal activity after single-dose administration in volunteers.

Ten healthy volunteers received 1 g of BRL-36650, a new formamido-penicillin derivative, given by intravenous infusion over 15 min. Levels in serum were measured microbiologically 30, 60, and 120 min after the start of the 15-min infusion and were (mean +/- standard deviation) 102.7 +/- 28.4, 59.7 +...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Pascual-Lopez, A, Van der Auwera, P, Lieppe, S, Klastersky, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3755314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.5.757
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