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Enhanced antiproliferative and apoptotic response to combined treatment of γ-tocotrienol with erlotinib or gefitinib in mammary tumor cells

BACKGROUND: Aberrant ErbB receptor signaling is associated with various types of malignancies. γ-Tocotrienol is a member of the vitamin E family of compounds that displays potent anticancer activity that is associated with suppression in ErbB receptor phosphorylation and mitogenic signaling. Erlotin...

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Hlavní autoři: Bachawal, Sunitha V, Wali, Vikram B, Sylvester, Paul W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841143/
https://ncbi.nlm.nih.gov/pubmed/20211018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-84
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