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'Genome order index' should not be used for defining compositional constraints in nucleotide sequences - a case study of the Z-curve

BACKGROUND: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gene transfer detection, and sequence analysis. Based on the Z-curve, a "genome order index," was proposed, which...

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Autors principals: Elhaik, Eran, Graur, Dan, Josić, Krešimir
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841071/
https://ncbi.nlm.nih.gov/pubmed/20158921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-10
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