Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion

[Image: see text] Munc18, an essential regulatory protein for intracellular membrane fusion mediated by SNAREs, is known for stabilizing the closed conformation of syntaxin through the interaction with the N-terminal Habc domain (amino acids 28−146) of syntaxin. In addition, Munc18 accelerates membr...

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Main Authors: Diao, Jiajie, Su, Zengliu, Lu, Xiaobing, Yoon, Tae-Young, Shin, Yeon-Kyun, Ha, Taekjip
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2010
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841011/
https://ncbi.nlm.nih.gov/pubmed/20300453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn900034p
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