Dynamic changes in the human methylome during differentiation

DNA methylation is a critical epigenetic regulator in mammalian development. Here, we present a whole-genome comparative view of DNA methylation using bisulfite sequencing of three cultured cell types representing progressive stages of differentiation: human embryonic stem cells (hESCs), a fibroblas...

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Bibliografiske detaljer
Main Authors: Laurent, Louise, Wong, Eleanor, Li, Guoliang, Huynh, Tien, Tsirigos, Aristotelis, Ong, Chin Thing, Low, Hwee Meng, Kin Sung, Ken Wing, Rigoutsos, Isidore, Loring, Jeanne, Wei, Chia-Lin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840979/
https://ncbi.nlm.nih.gov/pubmed/20133333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.101907.109
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