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Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens

The existence of thresholds for toxicants is a matter of debate in chemical risk assessment and regulation. Current risk assessment methods are based on the assumption that, in the absence of sufficient data, carcinogenesis does not have a threshold, while noncarcinogenic endpoints are assumed to be...

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Main Authors: BOOBIS, ALAN R., DASTON, GEORGE P., PRESTON, R. JULIAN, OLIN, STEPHEN S.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840875/
https://ncbi.nlm.nih.gov/pubmed/19690995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408390903098673
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