Prostaglandin F2α Represses IGF-I-Stimulated IRS1/Phosphatidylinositol-3-Kinase/AKT Signaling in the Corpus Luteum: Role of ERK and P70 Ribosomal S6 Kinase

Little is known about the early intracellular events that contribute to corpus luteum regression. Experiments were designed to determine the effects of prostaglandin F2α (PGF2α) on phosphatidylinositol-3-kinase (PI3K)/Akt signaling in the corpus luteum in vivo and in vitro. Treatment of midluteal-ph...

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Detalhes bibliográficos
Main Authors: Arvisais, Edward, Hou, Xiaoying, Wyatt, Todd A., Shirasuna, Koumei, Bollwein, Heinrich, Miyamoto, Akio, Hansen, Thomas R., Rueda, Bo R., Davis, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840803/
https://ncbi.nlm.nih.gov/pubmed/20160123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0312
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