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The CTLA4 -819 C/T and +49 A/G dimorphisms are associated with Type 1 diabetes in Egyptian children

BACKGROUND: Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. T cell proliferation is negatively regulated by cytotoxic lymphocyte antigen-4 (CTLA-4). CTLA-4 polymorphisms are associated with T1D in some but not all popul...

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Hlavní autoři: Saleh, Hatem Mohamed, Rohowsky, Nestor, Leski, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840795/
https://ncbi.nlm.nih.gov/pubmed/20300303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.45001
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