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Quantitative correlation between penicillin resistance and beta-lactamase activity specified by the R plasmids R1, R1 bla-45, and RP1 in Escherichia coli K-12.

A mutant of the R plasmid R1 which synthesizes a beta-lactamase with altered kinetic characteristics was isolated. The level of penicillin resistance specified by this plasmid was correctly predicted from the properties of the wild-type R1 according to a simple theoretical model published by Zimmerm...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Crowlesmith, I, Howe, T G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7004346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.5.675
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