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Characterization of beta-lactamase-deficient (bla) mutants of the R plasmid R1 in Escherichia coli K-12 and comparison with similar mutants of RP1.

Thirty-eight mutants of R1, an R plasmid specifying the type IIIa (TEM) beta-lactamase, were isolated; these mutants are partially or totally unable to synthesize the type IIIa beta-lactamase. The loss of beta-lactamase activity was associated with a reduction in the level of penicillin resistance c...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Crowlesmith, I, Howe, T G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7004345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.5.667
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