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Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae

Nonsense-mediated decay (NMD) degrades mRNA containing premature translation termination codons. In yeast, NMD substrates are decapped and digested exonucleolytically from the 5′ end. Despite the requirement for translation in recognition, degradation of nonsense-containing mRNA is considered to occ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hu, Wenqian, Petzold, Christine, Coller, Jeff, Baker, Kristian E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840703/
https://ncbi.nlm.nih.gov/pubmed/20118937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1734
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