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LEFTY, a Member of the Transforming Growth Factor-β Superfamily, Inhibits Uterine Stromal Cell Differentiation: A Novel Autocrine Role

LEFTY is expressed in normal endometrium in cells that decidualize. To understand the importance of this expression, we have studied the effect of LEFTY on decidualization in vitro and in vivo. Exposure of human uterine fibroblast (HuF) cells to recombinant LEFTY blocked the induction of the decidua...

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Main Authors: Tang, Meiyi, Naidu, Devendra, Hearing, Patrick, Handwerger, Stuart, Tabibzadeh, Siamak
格式: Artigo
語言:Inglês
出版: The Endocrine Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840686/
https://ncbi.nlm.nih.gov/pubmed/20056823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1081
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