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LEFTY, a Member of the Transforming Growth Factor-β Superfamily, Inhibits Uterine Stromal Cell Differentiation: A Novel Autocrine Role

LEFTY is expressed in normal endometrium in cells that decidualize. To understand the importance of this expression, we have studied the effect of LEFTY on decidualization in vitro and in vivo. Exposure of human uterine fibroblast (HuF) cells to recombinant LEFTY blocked the induction of the decidua...

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Detalhes bibliográficos
Main Authors: Tang, Meiyi, Naidu, Devendra, Hearing, Patrick, Handwerger, Stuart, Tabibzadeh, Siamak
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840686/
https://ncbi.nlm.nih.gov/pubmed/20056823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1081
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