Influence of extracellular K+ or Mg2+ on the stages of the antifungal effects of amphotericin B and filipin.

The macrolide heptaene amphotericin B (AmB) induced concentration-dependent effects on Saccharomyces cerevisiae which were separable into two distinct stages. At low concentrations the drug inhibited the growth of the yeast and reversible changed cell permeability to Na+ and K+. At high levels it wa...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Brajtburg, J, Medoff, G, Kobayashi, G S, Elberg, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1980
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7004343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.593
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