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A fast, single-vesicle fusion assay mimics physiological SNARE requirements

Almost all known intracellular fusion reactions are driven by formation of trans-SNARE complexes through pairing of vesicle-associated v-SNAREs with complementary t-SNAREs on target membranes. However, the number of SNARE complexes required for fusion is unknown, and there is controversy about wheth...

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Detalhes bibliográficos
Main Authors: Karatekin, Erdem, Di Giovanni, Jérôme, Iborra, Cécile, Coleman, Jeff, O'Shaughnessy, Ben, Seagar, Michael, Rothman, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840481/
https://ncbi.nlm.nih.gov/pubmed/20133592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914723107
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