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Topical Naltrexone Reverses Dry Eye and Restores Corneal Sensation in Diabetes Mellitus

OBJECTIVE: To determine if topical application of naltrexone (NTX), an opioid antagonist, restores tear production and corneal sensation in rats with diabetes. METHODS: Type 1 diabetes (DB) was induced with streptozotocin (STZ) in rats. Tear production was measured by the Schirmer's test, and c...

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Detalhes bibliográficos
Main Authors: Zagon, Ian S., Klocek, Matthew S., Sassani, Joseph W., McLaughlin, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840396/
https://ncbi.nlm.nih.gov/pubmed/19901212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archophthalmol.2009.270
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