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Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice

About 70% of hepatocellular carcinomas are known to express α-fetoprotein, which is normally expressed in fetal but not in adult livers. To induce herpes simplex virus-thymidine kinase expression in these cancer cells, we constructed an adeno-associated viral vector containing the HSV-TK gene under...

詳細記述

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書誌詳細
主要な著者: Su, Hua, Lu, Ronghua, Chang, Judy C., Kan, Yuet Wai
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC28403/
https://ncbi.nlm.nih.gov/pubmed/9391123
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