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Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis

D-Aspartic acid is abundant in the developing brain. We have identified and cloned mammalian aspartate racemase (DR), which converts L-aspartate to D-aspartate and colocalizes with D-aspartate in the brain and neuroendocrine tissues. Depletion of DR by retrovirus-mediated expression of short-hairpin...

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Hlavní autoři: Kim, Paul M., Duan, Xin, Huang, Alex S., Liu, Cindy Y., Ming, Guo-li, Song, Hongjun, Snyder, Solomon H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840285/
https://ncbi.nlm.nih.gov/pubmed/20133766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914706107
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