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Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis
D-Aspartic acid is abundant in the developing brain. We have identified and cloned mammalian aspartate racemase (DR), which converts L-aspartate to D-aspartate and colocalizes with D-aspartate in the brain and neuroendocrine tissues. Depletion of DR by retrovirus-mediated expression of short-hairpin...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840285/ https://ncbi.nlm.nih.gov/pubmed/20133766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914706107 |
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