EARLY T-CELL PRECURSOR LEUKEMIA: A SUBTYPE OF VERY HIGH-RISK ACUTE LYMPHOBLASTIC LEUKEMIA IDENTIFIED IN TWO INDEPENDENT COHORTS

BACKGROUND: Approximately one-fifth of children with acute T-lymphoblastic leukemia (T-ALL) succumb to the disease, suggesting unrecognized biologic heterogeneity that may contribute to drug resistance. We hypothesized that T-ALL originating from early T-cell precursors (ETPs), a recently defined su...

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Main Authors: Coustan-Smith, Elaine, Mullighan, Charles G., Onciu, Mihaela, Behm, Frederick G., Raimondi, Susana C., Pei, Deqing, Cheng, Cheng, Su, Xiaoping, Rubnitz, Jeffrey E., Basso, Giuseppe, Biondi, Andrea, Pui, Ching-Hon, Downing, James R., Campana, Dario
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840241/
https://ncbi.nlm.nih.gov/pubmed/19147408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(08)70314-0
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