Cell-free cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N.

Cell-free cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N by lytic enzyme extracts of Cephalosporium acremonium M-0198 was stimulated by ferrous ions. The optimum concentration of FeSO4 was 80 microM. No additional stimulation was observed with ascorbate, adenosine...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Sawada, Y, Baldwin, J E, Singh, P D, Solomon, N A, Demain, A L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1980
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7191691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.3.465
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