BDNF Val66Met is Associated with Introversion and Interacts with 5-HTTLPR to Influence Neuroticism

Brain-derived neurotrophic factor (BDNF) regulates synaptic plasticity and neurotransmission, and has been linked to neuroticism, a major risk factor for psychiatric disorders. A recent genome-wide association (GWA) scan, however, found the BDNF Val66Met polymorphism (rs6265) associated with extrave...

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Detalhes bibliográficos
Main Authors: Terracciano, Antonio, Tanaka, Toshiko, Sutin, Angelina R, Deiana, Barbara, Balaci, Lenuta, Sanna, Serena, Olla, Nazario, Maschio, Andrea, Uda, Manuela, Ferrucci, Luigi, Schlessinger, David, Costa, Paul T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840212/
https://ncbi.nlm.nih.gov/pubmed/20042999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.213
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