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Cationic Surface Modification of PLG Nanoparticles Offers Sustained Gene Delivery to Pulmonary Epithelial Cells

Biodegradable polymeric nanoparticles are currently being explored as a nonviral gene delivery system; however, many obstacles impede the translation of these nanomaterials. For example, nanoparticles delivered systemically are inherently prone to adsorbing serum proteins and agglomerating as a resu...

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Autores principales: BAOUM, ABDULGADER, DHILLON, NAVNEET, BUCH, SHILPA, BERKLAND, CORY
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840200/
https://ncbi.nlm.nih.gov/pubmed/19911425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21994
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