TGF-β regulates T-cell neurokinin-1 receptor internalization and function

Substance P (SP) is a proinflammatory mediator implicated in inflammatory bowel disease (IBD) and other inflammatory states. SP acts by stimulating the neurokinin-1 receptor (NK-1R) on T lymphocytes and other cell types, and regulates these cells in a complex interplay with multiple cytokines. The m...

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Main Authors: Beinborn, Martin, Blum, Arthur, Hang, Long, Setiawan, Tommy, Schroeder, Jonathan C., Stoyanoff, Korynn, Leung, John, Weinstock, Joel V.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840170/
https://ncbi.nlm.nih.gov/pubmed/20160079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905877107
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