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Three-dimensional structure of tropism-switching Bordetella bacteriophage
Bacteriophage BPP-1, which infects Bordetella species, can switch its specificity by mutations to the ligand-binding surface of its major tropism-determinant protein, Mtd. This targeted mutagenesis results from the activity of a phage-encoded diversity-generating retroelement. Purified Mtd binds its...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840154/ https://ncbi.nlm.nih.gov/pubmed/20160083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915008107 |
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