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Three-dimensional structure of tropism-switching Bordetella bacteriophage

Bacteriophage BPP-1, which infects Bordetella species, can switch its specificity by mutations to the ligand-binding surface of its major tropism-determinant protein, Mtd. This targeted mutagenesis results from the activity of a phage-encoded diversity-generating retroelement. Purified Mtd binds its...

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Библиографические подробности
Главные авторы: Dai, Wei, Hodes, Asher, Hui, Wong H., Gingery, Mari, Miller, Jeff F., Zhou, Z. Hong
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840154/
https://ncbi.nlm.nih.gov/pubmed/20160083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915008107
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