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Operation of the voltage sensor of a human voltage- and Ca(2+)-activated K(+) channel

Voltage sensor domains (VSDs) are structurally and functionally conserved protein modules that consist of four transmembrane segments (S1–S4) and confer voltage sensitivity to many ion channels. Depolarization is sensed by VSD-charged residues residing in the membrane field, inducing VSD activation...

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Hlavní autoři: Pantazis, Antonios, Gudzenko, Vadym, Savalli, Nicoletta, Sigg, Daniel, Olcese, Riccardo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840143/
https://ncbi.nlm.nih.gov/pubmed/20160086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911959107
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