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Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression
The type 4 melanocortin receptor MC4R, a key relay in leptin signaling, links central energy control to peripheral reserve status. MC4R activation in different brain areas reduces food intake and increases energy expenditure. Mice lacking Mc4r are obese. Mc4r is expressed by hypothalamic paraventric...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840120/ https://ncbi.nlm.nih.gov/pubmed/20160073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905190107 |
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