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CD44 attenuates activation of the Hippo signaling pathway and is a prime therapeutic target for glioblastoma

Glioblastoma multiforme (GBM) is the most aggressive brain tumor that, by virtue of its resistance to chemo- and radiotherapy, is currently incurable. Identification of molecules whose targeting may eliminate GBM cells and/or sensitize glioblastoma cells to cytotoxic drugs is therefore urgently need...

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Autori principali: Xu, Yin, Stamenkovic, Ivan, Yu, Qin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840073/
https://ncbi.nlm.nih.gov/pubmed/20197461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2505
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